I'm sure most of us can look back over our lives and remember males who seemed a bit on the feminine side, and females who seemed a bit on the masculine side. In fact, I'm sure many of us can remember people who were more than 'a bit' on the other side.
Another thing I'm sure of is that people who want to transgender want to do so for many different reasons. The best reason is perhaps that they have the body of a man or a woman and yet feel they have a mind of the opposite sex. Their essential self is literally trapped in the wrong body. At the other end of the scale, there are surely people who simply fancy a (somewhat drastic) change.
In many cases, the process of changing gender involves the use of drugs and cosmetic surgery in order to give the person a more convincing overall appearance as well as a complete change in intimate plumbing.
I've seen a great many such cases on TV and it has to be said that the finished result is more convincing in some cases than in others.
There is one person, however, who is (to my mind, at any rate) the absolute and utter living proof that a woman can be born in a male body and that is a young woman called Jackie (née Jason) McCauliffe who is perhaps better known as the piano-playing prostitute in the 1998 BBC TV fly-on-the-wall docusoap series "Paddington Green".
I would defy anybody to watch her and listen to her on TV or even to meet her and talk to her in real life, and come to the conclusion that she has not always been 100% female.
When she released a CD of her piano playing, she was interviewed on James Whale's radio programme and a camera followed her into the studio. James had been briefed that he would be interviewing a male-to-female transsexual but, when Jackie walked into his studio, he was absolutely gobsmacked and it was clear that he had the greatest difficulty believing she wasn't a "natural" woman.
He told her that he was aware that medical science could do wonders in the field of sexual transitioning then added, still disbelieving what he saw before him, "but you can't change your skeleton!"
Jackie just gave a little shrug and sat down for the interview.
PS. I found a posting on an Internet forum in which a girl who was at sixth-form college with the then Jason said he was a really nice lad - and she always envied his legs!