Anybody know of any obscure sitcoms that came and went without anybody noticing, but were actually pretty good? My two nominations would be "Action" from five or six years ago. This was about a movie producer played by Jay Mohr, and was very funny in a Larry Sanders kind of way. Alas, it only lasted about twelve episodes before being cancelled.
My other favourite lost gem is Bakersfield PD, another American sitcom, this time about an incompetent police force. This one managed to last a full series before having the plug pulled.