Having thought about it for some reason, here are my thoughts on some things I personally would address if I was going to make more of this show:
First, I would make the different tribes mix more, rather than being entirely separate entities. I thought it an odd choice and I'm not sure what keeping them separate was supposed to add?
Second, I would focus on the group of five Hollyoaks-esque characters and work on their comic personas more; what is it about each that is going to make people want to watch them and generate comedy? Like it or loathe it, it's obvious from the off who each Two Pints character is and what funny they are going to bring to the table each week.
I would drop the pretty boy and his girlfriend, they add nothing apart from being attractive to look at, and instead make the Community officer bloke the slouchy, trying not to be boring characters best friend.
I would also make it so that the kid trying to connect with his Dad was also hanging around the main group, trying to also connect with them, and failing.
I would think about dropping bits in peoples houses, and focus just on the pub and outside the pub.
A personal thing, but I would avoid the blasts of currently popular songs that blared out every time we changed to a new scene; it quickly becomes annoying and is already being done in other shows.
I think that's it.