I nominate Pulling which was canned after two series for absurd reasons to do with BBC Three's demographics and not because it had run out of steam or that Sharon Horgan no longer wanted to write or star in it.
Second one is This is David Lander with Stephen Fry which was a spoof investigative current affairs show and was years ahead of its time and didn't really get the recognition it deserved and would build up a much bigger ratings with today's more savvy audience.