Quote: Steve Sunshine @ 16th May 2015, 12:51 AM BSTBut he's ruined his own thread by being a 24 carat tosspot
Shock, horror(!)
Psoriasis Page 3
Quote: keewik @ 15th May 2015, 11:56 PM BSTMethotrexate is also a cancer drug. It was one of many things my younger son had for childhood leukaemia. Presumably it's for things that are to do with the immune system
Yes, it suppresses the immune system which of course brings all sorts of other problems.
Perhaps we should ask admin to open a 'medical discussion' forum. I was a bit taken aback when I saw this thread this morning, although there are always jokes to be made about afflictions so I suppose there is comedy value in there somewhere.
Further to my experience of psoriasis having had lived with someone (my wife) who has suffered from it for 40 years - and how do I know it is that long? Because it was the birth of my 40 year old son who caused it.
He was late and stressed in the womb, my wife became stressed so they had to get him out via a Caesar and from then on her condition started, because although he was perfectly fine after the birth, my wife had a bad time post op. and the condition started in her scalp.
She suffered from this for many years and then 20 years ago she took on a large guest house, which exacerbated her condition as the psoriasis spread over her body, especially her hands which became red raw with it.
Then four years ago she had a brain haemorrhage (stroke) and it all went downhill from there, although the hospital then came up with a course of Methotrexate which worked and cleared her condition quite quickly.
When she eventually came home she was checked regularly for liver damage with this powerful drug (a specialist told us last year that it was in effect a poison!!) and they tried to wean her off it but when they got it down to one tablet (2½ grams) it came back with a vengeance and so she is now back on 4 (10mg.) and the condition has cleared up again.
She tried various diets as suggested in a book my son bought her (Yes, Steve - most of what you said) and various creams, emollients etc., (which she still uses to supplement the drug) but the Methotrexate is the only thing that controls it. She has slight liver damage but nothing to worry about unduly and she says the relief she gets from the drug makes it all worthwhile.
I'm very proud of her as she has had a hell of a lot to contend with but remains cheerful.
Quote: Hercules Grytpype Thynne @ 16th May 2015, 11:49 AM BST(a specialist told us last year that it was in effect a poison!!)
I was told that too.
Quote: Hercules Grytpype Thynne @ 15th May 2015, 10:52 PM BSTMethotrexate, which was a drug developed for controlling arthritis, was found to also keep psoriasis under control, BUT it has a side effect of causing liver damage.
My wife has to have this checked every 3 months.
Someone I work with started using Methotrexate and it cleared their psoriasis right up, but it can be quite bad for you as you said. They don't use it anymore and just rely on creams instead.
Quote: Ben @ 16th May 2015, 2:20 PM BSTSomeone I work with started using Methotrexate and it cleared their psoriasis right up, but it can be quite bad for you as you said. They don't use it anymore and just rely on creams instead.
And good on them if they can control it that way, but it is not enough for my wife. I suppose there are different degrees of the problem.
My manager at the school I just retired from had bad rheumatoid arthritis and Methotrexate was/is the only answer for him. He told me that he tried to cut it back (from the 10mg, which seems to be the norm), but the fingers on his hands started to swell and curl into the palms. Terrible affliction.
Quote: Hercules Grytpype Thynne @ 16th May 2015, 4:29 PM BSTAnd good on them if they can control it that way, but it is not enough for my wife. I suppose there are different degrees of the problem.
Has your wife tried infliximab, humira or etanercept?
Kim Kardashian has Psoriarasas, doesn't seem to stop her doing her thing
I've had psoriasis for many years, I don't bother with any medication now, but use moisturising cream. It's often associated with genius.
Quote: beaky @ 16th May 2015, 7:08 PM BSTI've had psoriasis for many years, I don't bother with any medication now, but use moisturising cream. It's often associated with genius.
I've heard of moisturising cream being associated with many things, but never genius.
Maybe it helps his great big swollen, head full of brains?
Quote: Loopey @ 16th May 2015, 5:17 PM BSTHas your wife tried infliximab, humira or etanercept?
I've printed off the NHS sheets on these and see what the doctor says, thank you. My wife has read them and knew of a couple of them that are injections.
I'll let you know what we find out.
Quote: Stylee TingTing @ 16th May 2015, 9:20 PM BSTI don't know anything about Psoriasis - I'll have to start learning from scratch.
Well I'm itching to find out how you get on
Quote: Hercules Grytpype Thynne @ 16th May 2015, 9:35 PM BSTI've printed off the NHS sheets on these and see what the doctor says, thank you. My wife has read them and knew of a couple of them that are injections.
I'll let you know what we find out.
Good luck. Infliximab is given intravenously and it can be tricky to get funding in some areas, but if it's considered suitable it might be worth pursuing to have a break from mtx. Humira is usually a self administered injection either into tummy or thigh. I don't know anything about the other one but it has been mentioned to me in the past. Some people don't like infliximab on principle because it contains extract of mouse or somesuch.
Stress being a Psoriasis trigger can also be problematic.
With Psoriasis being quite stressful in itself.
It's a Scratch 22 situation